Showing posts with label mania. Show all posts
Showing posts with label mania. Show all posts

Thursday, May 28, 2009

How Mood and felt Energy are related to thought variability and speed

There is a recent article by Pronin and Jacobs, on the relationship between mood, thought speed and experience of 'mental motion' that builds up on their previous work.

Let us see how they describe thought speed and variability and what their hypothesis is:


1. The principle of thought speed. Fast thinking, which involves many thoughts per unit time, generally produces positive affect. Slow thinking, which involves few thoughts per unit time, generally produces less positive affect. At the extremes of thought speed, racing thoughts can elicit feelings of mania, and sluggish thoughts can elicit feelings of depression.
2. The principle of thought variability. Varied thinking generally produces positive affect, whereas repetitive thinking generally produces negative affect. This principle is derived in part from the speed principle: when thoughts are repetitive, thought speed (thoughts per unit time) diminishes. At its extremes, repetitive thinking can elicit feelings of depression (or anxiety), and varied thinking can elicit feelings of mania (or reverie).

Let me clarify at the outset that they are aware of the effects of though speed on variability and vice versa; as well as the effects of mood on felt energy and vice versa; thus they know that one can confound the other. Another angle they consider is the relationship between thought speed/variability i.e the form of thought and the contents of thought (whether having emotional salience or neutral) and investigated whether the effects of speed and variability were confounded with though content; they found negative evidence for this inetrcationist view.

Let me also clarify that I differ slightly (based on my interpreation of their data) from their original hypothesis, in the sense that I believe that their data shows that speed affects felt energy and variability affects affect and that the effects of speed on mood may be mediated by the effect of speed on felt energy and similarly the effect of variability on felt energy may be mediated by its effects on mood.

Thus my claim is that:

  1. Thought speed leads to more felt energy. Extremes of 'racing thoughts' leads to the manic feeling of being very energetic (when accompanied with positive mood, this may give rise to feelings of grandiosity- I have the energy to achieve anything), while also may lead to anxiety states (when accompanied with negative affect) in which one cannot really suppress a negative chain of thoughts - one following the other in fast succession, regarding the object of ones anxiety. The counterpart to this the state where thoughts come slowly (writer's block etc) and when accompanied with negative affect, this can easily be viewed as depression.
  2. Thought variability leads to more positive affect: Extremes of 'tangential thoughts' leads to the manic feeling of being in a good mood (when accompanied with high energy , this manifest as feelings of euphoria); while the same tangential thoughts when accompanied by low felt energy may actually be felt as serenity/ calmness/ reverie. The counterpart to this is the state of thoughts that are stuck in a rut - when accompanied with low energy this leads to feelings of depression and sadness.

Thus, to put simply : there are two dimensions one needs to take care of - mood (thought variability) x energy (thought speed) and high and low extremes on these dimensions are all opposites of their counterpart.

Before we move on, I'll let the authors present their other two claims too:
3. The combination principle. Fast, varied thinking prompts elation; slow, repetitive thinking prompts dejection. When speed and variability oppose each other, such that one is low and the other high, individuals’ affective experience will depend on factors including which one of the two factors is more extreme. The psychological state elicited by such combinations can vary apart from its valence, as shown in Figure 1. For example, repetitive thinking can elicit feelings of anxiety rather than depression if that repetitive thinking is rapid. Notably, anxious states generally are more energetic than depressive states. Moreover, just as fast-moving physical objects possess more energy than do identical slower objects, fast thinking involves more energy (e.g., greater wakefulness, arousal, and feelings of energy) than does slow thinking.
4. The content independence principle. Effects of thought speed and variability are independent of the specific nature of thought content. Powerful affective states such as depression and anxiety have been traced to irrational and dysfunctional cognitions (e.g., Beck, 1976). According to the independence principle, effects of mental motion on mood do not require any particular type of thought content.

They review a number of factors and studies that all point to a causal link between thought speed and energy and between thought variability and mood. More importantly they show the independent effects of though speed and variability from the effects of thought content on mood. I'll not go into the details of the studies and experiments they performed, as their article is available freely online and one can read for oneself (it makes for excellent reading); suffice it to say that I believe they are on the right track and have evidence to back their claims.

What are the implications of this:

The speed and repetition of thoughts, we suggest, could be manipulated in order to alter and alleviate some of the mood and energy symptoms of mental disorders. The slow and repetitive aspects of depressive thinking, for example, seem to contribute to the disorder’s affective symptoms (e.g., Ianzito et al., 1974; Judd et al., 1994; Nolen-Hoeksema, 1991; Philipp et al., 1991; Segerstrom et al., 2000). Thus, techniques that are effective in speeding cognition and in breaking the cycle of repetitive thought may be useful in improving the mood and energy levels of depressed patients. The potential of this sort of treatment is suggested by Pronin and Wegner’s (2006) study, in which speeding participants’ cognitions led to improved mood and energy, even when those cognitions were negative, self-referential, and decidedly depressing. It also is suggested by Gortner et al.’s (2006) finding that an expressive writing manipulation that decreased rumination (even while inducing thoughts about an upsetting experience) rendered recurrent depression less likely.

There also is some evidence suggesting that speeding up even low-level cognition may improve mood in clinically depressed patients. In one experiment, Teasdale and Rezin (1978) instructed depressed participants to repeat aloud one of four letters of the alphabet (A, B, C, or D) presented in random order every 1, 2, or 4 s. They found that those participants required to repeat the letters at the fastest rate experienced the most reduction in depressed mood. Similar techniques could be tested for the treatment of other mental illnesses. For example, manipulations might be designed to decrease the mental motion of manic patients, perhaps by introducing repetitive and slow cognitive stimuli. Or, in the case of anxiety disorders, it would be worthwhile to test interventions aimed at inducing slow and varied thought (as opposed to the fast and repetitive thought characteristic of anxiety). The potential effectiveness of such interventions is supported by the fact that mindfulness meditation, which involves slow but varied thinking, can lessen anxiety, stress, and arousal.
 hat tip: Ulterior Motives

ResearchBlogging.org
Pronin, E., & Jacobs, E. (2008). Thought Speed, Mood, and the Experience of Mental Motion Perspectives on Psychological Science, 3 (6), 461-485 DOI: 10.1111/j.1745-6924.2008.00091.x
Pronin, E., & Wegner, D. (2006). Manic Thinking: Independent Effects of Thought Speed and Thought Content on Mood Psychological Science, 17 (9), 807-813 DOI: 10.1111/j.1467-9280.2006.01786.x

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Friday, April 03, 2009

Low Mood and Risk Aversion: a poor State outcome?

Daniel Nettle, writes an article in Journal Of Theoretical Biology about the evolution of low mood states. Before I get to his central thesis, let us review what he reviews:

Low mood describes a temporary emotional and physiological state in humans, typically characterised by fatigue, loss of motivation and interest, anhedonia (loss of pleasure in previously pleasurable activities), pessimism about future actions, locomotor retardation, and other symptoms such as crying.
...
This paper focuses on a central triad of symptoms which are common across many types of low mood, namely anhedonia, fatigue and pessimism. Theorists have argued that, whereas their opposites facilitate novel and risky behavioural projects. These symptoms function to reduce risk-taking. They do this, proximately, by making the potential payoffs seem insufficiently rewarding (anhedonia), the energy required seem too great (fatigue), or the probability of success seem insufficiently high (pessimism). An evolutionary hypothesis for why low mood has these features, then, is that is adaptive to avoid risky behaviours when one is in a relatively poor current state, since one would not be able to bear the costs of unsuccessful risky endeavors at such times .

I would like to pause here and note how he has beautifully summed up the low mood symptoms and key features; taking liberty to define using my own framework of Value X Expectancy and distinction between cognitive('wanting') and behavioral ('liking') side of things :
  • Anhedonia: behavioral inability to feel rewarded by previously pleasurable activities. Loss of 'liking' following the act. Less behavioral Value assigned.
  • Loss of motivation and interest: cognitive inability to look forward to or value previously desired activities. Loss of 'wanting' prior to the act. Less cognitive Value assigned.
  • Fatigue: behavioral inability to feel that one can achieve the desired outcome due to feelings that one does not have sufficient energy to carry the act to success. Less behavioral Expectancy assigned.
  • Pessimism: cognitive inability to look forward to or expect good things about the future or that good outcomes are possible. Less cognitive Expectancy assigned.
The reverse conglomeration is found in high mood- High wanting and liking, high energy and outlook. Thus, I agree with Nettle fully that low mood and high mood are defined by these opposed features and also that these features of low and high mood are powerful proximate mechanisms that determine the risk proneness of the individual: by subjectively manipulating the Value and Expectancy associated with an outcome, the high and low mood mediate the risk proneness that an organism would display while assigning a utility to the action. Thus, it is fairly settled: if ultimate goal is to increase risk-prone behavior than the organism should use the proximate mechanism of high mood; if the ultimate goal is to avoid risky behavior, then the organism should display low mood which would proximately help it avoid risky behavior.

Now let me talk about Nettle's central thesis. It has been previously proposed in literature that low mood (and thus risk-aversion) is due to being in a poor state wherein one can avoid energy expenditure (and thus worsening of situation) by assuming a low profile. Nettle plays the devil's advocate and argues that an exactly opposite argument can be made that the organism in a poor state needs to indulge in high risk (and high energy) activities to get out of the poor state. Thus, there is no a prior reason as to why one explanation may be more sound than the other. To find out when exactly high risk behavior pay off and when exactly low risk behaviors are more optimal, he develops a model and uses some elementary mathematics to derive some conclusions. He, of course , bases his model on a Preventive focus, whereby the organism tries to minimize getting in a state R , which is sub-threshold. He allows the S(t) to be maximized under the constraint that one does not lose sight of R. I'll not go into the mathematics, but the results are simple. When there is a lot of difference between R (dreaded state) and S (current state), then the organism adopts a risky behavioral profile. when the R and S are close, he maintains low risk behavior, however when he is in dire circumstances (R and S are very close) then risk proneness again rises to dramatic levels. To quote:

The model predicts that individuals in a good state will be prepared to take relatively large risks, but as their state deteriorates, the maximum riskiness of behaviour that they will choose declines until they become highly risk-averse. However, when their state becomes dire, there is a predicted abrupt shift towards being totally risk-prone. The switch to risk-proneness at the dire end of the state continuum is akin to that found near the point of starvation in the original optimal foraging model from which the current one is derived (Stephens, 1981). The graded shift towards greater preferred risk with improving state is novel to this model, and stems from the stipulation that if the probability of falling into the danger zone in the next time step is minimal, then the potential gain in S at the next time step should be maximised. However, a somewhat similar pattern of risk proneness in a very poor state, risk aversion in an intermediate state, and some risk proneness in a better state, is seen in an optimal-foraging model where the organism has not just to avoid the threshold of starvation, but also to try to attain the threshold of reproduction (McNamara et al., 1991). Thus, the qualitative pattern of results may emerge quite generally from models using different assumptions.

Nettle, then extrapolates the clinical significance from this by proposing that 'agitated' / 'excited' depression can be explained as when the organism is in dire straits and has thus become risk-prone. He also uses a similar logic for dysphoric mania although I don't buy that. However, I agree that euphoric mania may just be the other extreme of high mood and more risk proneness and goal achievements; while depression the normal extreme of low mood and adverse circumstances and risk aversion. To me this model ties up certain things we know about life circumstances and the risk profile and mood tone of people and contributes to deepening our understanding.
ResearchBlogging.org
Nettle, D. (2009). An evolutionary model of low mood states Journal of Theoretical Biology, 257 (1), 100-103 DOI: 10.1016/j.jtbi.2008.10.033

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Wednesday, March 25, 2009

The bipolar phenotype: Excessive self-regulatory focus?

In my last post I had hinted that bipolar mania and depression may both be characterized by an excessive and overactive self-regulatory focus: with promotion focus being related to Mania and prevention focus being related to depression. It is important to pause and note that the bipolar propensity is towards more self-referential goal-directed activity resulting in excessive use of self-regulatory focus. To clarify, I am sticking my neck out and claiming that depression is marked by an excessive obsession with self-oriented goal directed activities- but with a preventive focus thus focusing more on self's responsibilities and duties , obligations etc with respect to other near and dear ones. Mania on the other hand, also has excessive self-oriented goal-directed focus, but the focus is promotional with obsession with hopes, aspirations etc, which are relatively more inward-focused and not too much dependent on significant others.

Thus, my characterization of depression as a state where regulatory reference is negative (one is focused on avoiding landing up in a negative end-state like being a burden on others), the regulatory anticipation is negative ( one anticipates pain as a result of almost any act one may perform and thus dreads day-to-day- activity) and the regulatory focus is negative (preventive focus whereby one is more concerned with duties and obligations to perform and security is a paramount need). The entire depressive syndrome can be summed up as an over activity of avoidance based mechanisms. However, please note that still there is an excess of self-referential/self-focused thinking and one is greatly motivated (although might be lacking energy) to bridge the differences between the real self and the 'ought' self. One can say that one's whole life revolves around trying to become the 'ought' self, or rather one conceptualizes oneself in terms of the 'ought' self.

Contrast this with Mania, where the regulatory reference is positive (one is focused on achieving something grandiose ) , regulatory anticipation is positive (one feels in control and believes that only good things can happen to the self) and regulatory focus is positive (promotional focus whereby one is more concerned with hopes, aspirations etc and growth / actualization needs). Still, juts like in depression there is an excess of focus on self and one is greatly motivated (and also has the energy) to bridge the difference between the real and the 'ideal' self. One can say that one's whole life revolves around trying to become the 'ideal' self , or rather one conceptualizes oneslef in terms of an 'ideal' self.

What can we predict from above: we know that brain's default network is involved in self-focused thoughts and ruminations. We can predict, and know for a fact, that the default network is overactive in schizophrenics (and thus by extension in bipolars who I believe have the same underlying pathology, at least as far as psychotic spectrum is concerned)and thus we can say with confidence that indeed the regulatory focus should be high for bipolars and this should be correlated with default network activity. We can also predict that during the Manic phase, the promotion focus related neural network should be more active and in depressive phase the prevention-related areas of the brain should be more active. this last hypothesis still needs experimentation, but lets backtrack a bit and first look at the neural correlates of the promotion and preventive regulatory self-focus.

For this, I refer the readers to an , in my view, important study that tried to dissociate the medial PFC and PCC activity (both of which belong to the default network) while people engaged in self-reflection. Here is the abstract of the study:

Motivationally significant agendas guide perception, thought and behaviour, helping one to define a ‘self’ and to regulate interactions with the environment. To investigate neural correlates of thinking about such agendas, we asked participants to think about their hopes and aspirations (promotion focus) or their duties and obligations (prevention focus) during functional magnetic resonance imaging and compared these self-reflection conditions with a distraction condition in which participants thought about non-self-relevant items. Self-reflection resulted in greater activity than distraction in dorsomedial frontal/anterior cingulate cortex and posterior cingulate cortex/precuneus, consistent with previous findings of activity in these areas during self-relevant thought. For additional medial areas, we report new evidence of a double dissociation of function between medial prefrontal/anterior cingulate cortex, which showed relatively greater activity to thinking about hopes and aspirations, and posterior cingulate cortex/precuneus, which showed relatively greater activity to thinking about duties and obligations. One possibility is that activity in medial prefrontal cortex is associated with instrumental or agentic self-reflection, whereas posterior medial cortex is associated with experiential self-reflection. Another, not necessarily mutually exclusive, possibility is that medial prefrontal cortex is associated with a more inward-directed focus, while posterior cingulate is associated with a more outward-directed, social or contextual focus.

The authors then touch upon something similar to what I have said above, that one can be too much planful or goal-directed (bipolar propensity) , but it would still make sense to find whether the focus is promotional or preventive. To quote:

The idea of variation in individuals’ regulatory focus highlights the difference between agendas and traits; two people could both be described by the trait ‘planful’, but planful about what? A person with a predominantly promotion focus would be more likely to be planful about attaining positive rewards or outcomes, while a person with a predominantly prevention focus would be more likely to be planful about avoiding negative events or outcomes. Although a promotion or prevention focus may dominate, the aspects of the self that are active change dynamically across situations (e.g. Markus and Wurf, 1987), thus most individuals have both promotion and prevention agendas. For example, the same person can hold both the hope of becoming rich (a promotion agenda) and the duty to support an aging parent (a prevention agenda), or the aspiration to be a good citizen and the obligation to be a well-informed voter. As individuals, hopes and aspirations and duties and obligations make up a large part of our mental life and constitute the motivational scaffolding for much of our behaviour.


Now comes the study design:

The present studies investigated neural activity when participants were asked to think about self-relevant agendas related to either a promotion (think about your hopes and aspirations) or prevention (think about your duties and obligations) focus. We compared neural activity associated with thinking about these two different types of self-relevant agendas and with thinking about non-self-relevant topics (distraction). We expected greater activity in anterior and/or posterior medial regions associated with these two self-reflection conditions compared with the distraction control condition because thinking about one's agendas, like thinking about one's traits, is self-referential. Such a finding would also be consistent, for example, with Luu and Tucker's (2004) proposal that both anterior cingulate and posterior cingulate cortex contribute to action regulation by representing goals and expectancies.

And this is what they found:


A double dissociation was found when participants were cued to think about promotion and prevention agendas on different trials for the first time during scanning (Experiment 2) and when they spent several minutes thinking about either promotion or prevention agendas before scanning (Experiment 1), indicating that it results from what participants are thinking about during the scan and not from some general effect (e.g. mood) carried over from the pre-scan period of self-reflection,

Here is what they discuss:

In short, the double dissociation between medial PFC and anterior/inferior medial posterior areas and our two self-reflection conditions indicates that these brain areas serve somewhat different functions during self-focus. There are a number of interesting possibilities that remain to be sorted out. Differential activity in these anterior medial and posterior medial regions as a function of the types of agendas participants were asked to think about could reflect: (i) differences in the representational content in the specific features of agendas, schemas, possible selves and so forth that constitute hopes and aspirations on the one hand and duties and obligations on the other (cf. Luu and Tucker, 2004); (ii) differences in the type(s) of component processes these agendas are likely to engage and/or the representational content they are likely to activate, for example, discovering new possibilities (hopes) vs retrieving episodic memories (e.g. Maddock et al., 2001) of past commitments (duties); (iii) differences in affective significance of hopes and aspirations (attaining the positive) and duties and obligations (avoiding the negative, Higgins, 1997; 1998); (iv) different aspects of the subjective experience of self, such as the subjective experience of control (an instrumental self) vs the subjective experience of awareness (an experiential self; Johnson, 1991; Johnson and Reeder, 1997; compare, e.g. Searle, 1992 and Weiskrantz, 1997, vs Shallice, 1978 and Umilta, 1988); (v) differences in the social significance of hopes and aspirations (more individual) and duties and obligations (involving others). This last possibility is suggested by findings linking the posterior cingulate with taking the perspective of another (Jackson et al., 2006). It may be that thinking about duties and obligations (a more outward focus) tends to involve more perspective-taking than does thinking about hopes and aspirations (a more inward focus). The greater number of mental/emotional references from the promotion group on the pre-scan essay and the tendency for a greater number of references to others from the prevention group are consistent with the hypothesis that medial PFC activity is associated with a more inward focus whereas posterior cingulate/precuneus activity is associated with a more outward, social focus. Clarifying the basis of the similarities and differences between neural activation associated with thinking about hopes and aspirations vs duties and obligations would begin to help differentiate the relative roles of brain regions in different types of self-reflective processing.

They do discuss clinical significance of their studies , but not in terms I would have loved to. I would like to see, whether there is state/trait hyperactivity and dissociation between the mPFC and PCC activation when the variable of depressive episode or manic episode subject is introduced. I'll place my bets that there would be an interaction between the type of episode and the over activity in the corresponding default-brain regions; but would like to see that data collected.

So my thesis is that the self-reflective and focused default network is overactive in biploar/psychotic spectrum people, but a bias or tilt towards promotion or preventive focus leads to their recurring and periodic episdoes of mania and depression.

Lastly let me touch upon affect in these state and what Higgins had to say about this in his paper covered yesterday. Higgins proposed that bipolar is due to a promotional focus, with mania induced when there is not much mismatch (or awareness of mismatch) between the ideal and real self; while depression or sadness and melancholia induced when one becomes aware of the discrepancy between the ideal and the real self. He proposes that 'ought' and real self discrepancy leads to anxiety and nervousness/ agitation; while a preventive focus and congruency between 'ought' and real leads to calmness/quiescence.

I disagree with his formulations, in as much as I differentiate between a regulatory focus and the corresponding awareness of discrepancies in that direction. To Higgins they are the same; if someone has a promotional focus , he would also be more aware of the discrepancies between his ideal and real self and thus be saddened. I disagree. I believe that if one has a promotional focus one is driven by goals to make the resl self as close to the ideal self as possible and if one is not able to do so, one would use defense mechanisms to delude oneself , but will not admit to its reality, as the reality of incongruence along the focused dimension is too painful. However, because on is consciously focused on promotions, one would be aware of trade-offs and will acknowledge to himself that his 'ought' self, which anyway is not too important for his self-concept, is not congruent to the real self. Thus, one wit a predominant promotion focus may be painfully aware of the discrepancy between his 'ought' and real self and thus might be nervous, agitated/ irritable- all symptoms of Mania.

A depressive person on the other hand has a predominant preventive focus and all actions/ ruminations are driven by responsibilities and obligations. Here acknowledging to oneself that one has failed in meeting obligations may be catastrophic so one will try to delude oneself that one is closer to the 'ought' self than is the case. However, one may not require any defense mechanisms when judging the discrepancy between the 'ideal' and real self as that 'ideal' self is no longer a matter of life and death! One would be aware that one is not focusing too much on hopes and aspirations and thus feel despondent/ sad/ melancholic - again classical symptoms of depression. Yet, despite the affect of sadness, all rumination would be focused on 'ought' self and thus the content be of guilt, duties, burden, responsibilities, etc.

I'm sure there is some grain of truth in my formulation, but wont be able to state emphatically unless the above proposed dissociation study involving default region and bipolar people is done. If one of you decide to do that, do let me know the results, even if they contradict the thesis.

ResearchBlogging.org
Johnson, M. (2006). Dissociating medial frontal and posterior cingulate activity during self-reflection Social Cognitive and Affective Neuroscience, 1 (1), 56-64 DOI: 10.1093/scan/nsl004
Higgins, E. T. (1997). Beyond pleasure and pain American Psychologist (52), 1280-1300

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Tuesday, March 24, 2009

Beyond pleasure and pain: promotion, prevention, desire and dread.

The hedonic principle says that we are motivated to approach pleasure and avoid pain. This, as per Higgins is too simplistic a formulation. He supplants this with his concepts of regulatory focus, regulatory anticipation and regulatory reference. That is too much of jargon for a single post, but let us see if we can make sense.

First, let us conceptualize a desired end-state that an organism wants to be in- say eating food and satisfying hunger. This desired end-state becomes the current goal of the organism and leads to gold-directed behavior. Now, it is proposed that given this desired end-state, the organism has two ways to go about achieving or moving towards the end-state. If the organism has promotion or achievement self-regulation focus, then it will be more sensitive to whether the positive outcome is achieved or not and will thus have an approach orientation whereby it would try to match his next state to the desired state or try approaching the desired end-sate as close as possible. On the other hand, if the organism has a prevention or safety self-regulation focus, then it will be more sensitive to the negative outcome as to whether it becomes worse off after the behavior and will have an avoidance orientation whereby it would try to minimize the mismatch between his next state and the desired state. Thus given n next states with different food availability , the person with promotion focus will choose a next state that is as close, say within a particular threshold, to the desired state of satiety ; while the person with the prevention focus will be driven by avoiding all the sates that have a sub-threshold food availability and are thus mis-matched with the end-goal of satiety. thus, the number and actual states which are available for choosing form are different for the two groups: the first set is derived from whether the states are within a particular range of the end-state; the second set is derived from excluding all the states that are not within a particular range of the end-state. Put this way it is easy to see, that these strategies of promotion or prevention focus, place different cognitive and computational demands: the former requires explortation/ maximizing, the other may be satisfied by satisficing. (see my earlier post on exploration/ exploitation and satisficers / maximisers where I believe I was slightly mistaken).

Now, that I have explained in simple terms (hopefully) the concepts of self-regulatory focus, let me quote from the article and show how Higgins arrives at the same.

The theory of self-regulatory focus begins by assuming that the hedonic principle should operate differently when serving fundamentally different needs, such as the distinct survival needs of nurturance (e.g., nourishment) and security (e.g., protection). Human survival requires adaptation to the surrounding environment, especially the social environment (see Buss, 1996). To obtain the nurturance and security that children need to survive, children must establish and maintain relationships with caretakers who provide them with nurturance and security by supporting, encouraging, protecting, and defending them (see Bowlby, 1969, 1973). To make these relationships work, children must learn how their appearance and behaviors influence caretakers' responses to them (see Bowlby, 1969; Cooley, 1902/1964; Mead, 1934; Sullivan, 1953). As the hedonic principle suggests,children must learn how to behave in order to approach pleasure and avoid pain. But what is learned about regulating pleasure and pain can be different for nurturance and security needs. Regulatory-focus theory proposes that nurturance-related regulation and security-related regulation differ in regulatory focus. Nurturance-related regulation involves a promotion focus, whereas security related regulation involves a prevention focus.
.....
People are motivated to approach desired end-states, which could be either promotion-focus aspirations and accomplishments or prevention-focus responsibilities and safety. But within this general approach toward desired end-states, regulatory focus can induce either approach or avoidance strategic inclinations. Because a promotion focus involves a sensitivity to positive outcomes (their presence and absence), an inclination to approach matches to desired end-states is the natural strategy for promotion self-regulation. In contrast, because a prevention focus involves a sensitivity to negative outcomes (their absence and presence), an inclination to avoid mismatches to desired end-states is the natural strategy for prevention self-regulation (see Higgins, Roney, Crowe, & Hymes, 1994).

Figure 1 (not shown here, go read the article for the figure) summarizes the different sets of psychological variables discussed thus far that have distinct relations to promotion focus and prevention focus (as well as some variables to be discussed later). On the input side (the left side of Figure 1), nurturance needs, strong ideals, and situations involving gain-nongain induce a promotion focus, whereas security needs, strong oughts, and situations involving nonloss-loss induce a prevention focus. On the output side (the right side of Figure 1), a promotion focus yields sensitivity to the presence or absence of positive outcomes and approach as strategic means, whereas a prevention focus yields sensitivity to the absence or presence of negative outcomes and avoidance
as strategic means.
Higgins then goes on describing many experiments that support this differential regulations focus and how that is different from pleasure-pain valence based approaches. He also discusses the regulatory focus in terms of signal detection theory and here it is important to note that promotion focus leads to leaning towards (being biased towards) increasing Hits and reducing Misses ; while prevention focus means leaning more towards increasing correct rejections and reducing or minimizing false alarms. Thus,a promotion focus individual is driven by finding correct answers and minimizing errors of omission; while a preventive focused person is driven by avoiding incorrect answers and minimizing errors of commission. In Higgin's words:

Individuals in a promotion focus, who are strategically inclined to approach matches to desired end-states, should be eager to attain advancement and gains. In contrast, individuals in a prevention focus, who are strategically inclined to avoid mismatches to desired end-states, should be vigilant to insure safety and nonlosses. One would expect this difference in self-regulatory state to be related to differences in strategic tendencies. In signal detection terms (e.g., Tanner & Swets, 1954; see also Trope & Liberman, 1996), individuals in a state of eagerness from a promotion focus should want, especially, to accomplish hits and to avoid errors of omission or misses (i.e., a loss of accomplishment). In contrast, individuals in a state of vigilance from a prevention focus should want, especially, to attain correct rejections and to avoid errors of commission or false alarms (i.e., making a mistake). Therefore, the strategic tendencies in a promotion focus should be to insure hits and insure against errors of omission, whereas in a prevention focus, they should be to insure correct rejections and insure against errors of commission .

He next discusses Expectancy x Value effects in utility research. Basically , whenever one tries to decide between two or more alternative actions/ outcomes, one tries to find the utility of a particular decision/ behavioral act based on both the value and expectance of the outcome. Value means how desirable or undesirable (i.e what value is attached) that outcome is to that person. Expectancy means how probable it is that the contemplated action (that one is deciding to do) would lead to the outcome. By way of an example: If I am hungry, I want to eat food. Lets say there are two actions or decisions that have different utility that can lead to my hunger reduction. The first involves begging for food from the shopkeeper; the second involves stealing the food from the shopkeeper. The first may be having positive value (begging might not be that embarrassing) , but low expectancy (the shopkeeper is miserly and unsympathetic) ; while the second act may have negative value (I believe that stealing is wrong and would like to avoid that act) but high expectancy (I am sure I'll be able to steal the food and fulfill my hunger). the utility I impart to the two acts may determine what act I eventually decide to indulge in.

Higgins touches on research that showed that Expectancy X value have a multiplicative effect i.e as expectancy increases, and value increases the motivation to take that decision/ course of action increases non-linearly. He clarifies that this interaction effect is seen in promotion focus , but not in preventive focus:

Expectancy-value models of motivation assume not only that expectancy and value have an impact on goal commitment as independent variables but also that they combine multiplicatively (Lewin, Dembo, Festinger, & Sears, 1944; Tolman, 1955; Vroom, 1964; for a review, see Feather, 1982). The multiplicative assumption is that as either expectancy or value increases, the impact of the other variable on commitment increases. For example, it is assumed that the effect on goal commitment of higher likelihood of goal attainment is greater for goals of higher value. This assumption reflects the notion that the goal commitment involves a motivation to maximize the product of value and expectancy, as is evident in a positive interactive effect of value and expectancy. This maximization prediction is compatible with the hedonic or pleasure principle because it suggests that people are motivated to attain as much pleasure as possible.
Despite the almost universal belief in the positive interactive effect of value and expectancy, not all studies have found this effect empirically (see Shah & Higgins, 1997b). Shah and Higgins proposed that differences in the regulatory focus of decision makers might underlie the inconsistent findings in the literature. They suggested that making a decision with a promotion focus is more likely to involve the motivation to maximize the product of value and expectancy. A promotion focus on goals as accomplishments should induce an approach-matches strategic inclination to pursue highly valued goals with the highest expected utility, which maximizes Value × Expectancy. Thus, the positive interactive effect of value and expectancy assumed by classic expectancy-value models should increase as promotion focus increases.
But what about a prevention focus? A prevention focus on goals as security or safety should induce an avoid-mismatches strategic inclination to avoid all unnecessary risks by striving to meet only responsibilities that are clearly necessary. This strategic inclination creates a different interactive relation between value and expectancy. As the value of a prevention goal increases, the goal becomes a necessity, like the moral duties of the Ten Commandments or the safety of one's child. When a goal becomes a necessity, one must do whatever one can to attain it, regardless of the ease or likelihood of goal attainment. That is, expectancy information becomes less relevant as a prevention goal becomes more like a necessity. With prevention goals, motivation would still generally increase when the likelihood of goal attainment is higher, but this increase would be smaller for high-value goals (i.e., necessities) than low-value goals. Thus, the second prediction was that the positive interactive effect of value and expectancy assumed by classic expectancy value models would not be found as prevention focus increased. Specifically, as prevention focus increases, the interactive effect of value and expectancy should be negative.


And that is exactly what they found! the paper touches on many other corroborating readers and the interested reader can go to the source for more. Here I will now focus on his concepts of regulatory expectancy and regulatory reference.

Regulatory Reference is the tendency to be either driven by positive and desired end-states as a reference end-point and a goal; or to be driven by negative and undesired end-states as goals that are most prominent. For example, eating food is a desirable end-state; while being eaten by others is a undesired end-sate. now an organism may be driven by the end-sate of 'getting food' and thus would be regulating approach behavior of how to go about getting food. It is important to contrast this with regulatory focus; while searching for food, it may have promotion orientation focusing on matching the end state; or may have prevention focus i.e avoiding states that don't contain food; but it is still driven by a 'positive' or desired end-state. On the other hand, when the regulatory reference is a negative or undesirable end-state like 'becoming food', then avoidance behavior is regulated i.e. behavior is driven by avoiding the end-state. Thus, any state that keeps one away from 'being eaten' is the one that is desired; this may involve promotion focus as in approaching states that are opposite of the undesired state and provide safety from predator; or it may have a prevention focus as in avoiding states that can lead one closer to the undesired end-state. In words of Higgins:
Inspired by these latter models in particular, Carver and Scheier (1981, 1990) drew an especially clear distinction between self-regulatory systems that have positive versus negative reference values. A self-regulatory system with a positive reference value has a desired end state as the reference point. The system is discrepancy reducing and involves attempts to move one's (represented) current self-state as close as possible to the desired end-state. In contrast, a self-regulatory system with a negative reference value has an undesired end-state as the reference point. This system is discrepancy-amplifying and involves attempts to move the current self-state as far away as possible from the undesired end-state.

To me Regulatory Reference is similar to Value associated with a utility decision and determines whether when we are choosing between different actions/ goals , the end-states or goals have a positive connotation or a negative connotation.

That brings us to Regulatory anticipation: that is the now well-known Desire/ dread functionality of dopamine mediated brain regions that are involved in anticipation of pleasure and pain and drive behavior. This anticipation of pleasure or pain is driven by our Expectancies of how our actions will yield the desired/undesired outcomes and can be treated as the equivalent to Expectancy in the Utility decisions. The combination of independent factors of regulatory reference and regulatory anticipation will drive what end-state or goal is activated to be the next target for the organism. Once activated, its tendencies towards promotion focus or prevention focus would determine how it strategically uses approach/ avoidance mechanisms to archive that goal or move towards the end-state. Let us also look at regulatory anticipation as described by higgins:

Freud (1920/1950) described motivation as a "hedonism of the future." In Beyond the Pleasure Principle (Freud, 1920/1950), he postulated that people go beyond total control of the "id" that wants to maximize pleasure with immediate gratification to regulating as well in terms of the "ego" or reality principle that avoids punishments from norm violations. For Freud, then, behavior and other psychical activities were driven by anticipations of pleasure to be approached (wishes) and anticipations of pain to be avoided (fears). Lewin (1935) described how the "prospect" of reward or punishment is involved in children learning to produce or suppress, respectively, certain specific behaviors (see also Rotter, 1954). In the area of animal learning, Mowrer (1960) proposed that the fundamental principle underlying motivated learning was regulatory anticipation, specifically, approaching hoped-for desired end-states and avoiding feared undesired endstates. Atkinson's (1964) personality model of achievement motivation also proposed a basic distinction between self-regulation in relation to "hope of success" versus "fear of failure." Wicker, Wiehe, Hagen, and Brown (1994) extended this notion by suggesting that approaching a goal because one anticipates positive affect from attaining it should be distinguished from approaching a goal because one anticipates negative affect from not attaining it. In cognitive psychology, Kahneman and Tversky's (1979) "prospect theory" distinguishes between mentally considering the possibility of experiencing pleasure (gains) versus the possibility of experiencing pain (losses).

Why I have been dwelling on this and how this fits into the larger framework: Wait for the next post, but the hint is that I believe that bipolar mania as well as depression is driven by too much goal-oriented activity- in mania the focus being promotion; while in depression the focus being preventive; Higgins does discuss mania and depression in his article, but my views differ and would require a new and separate blog post. Stay tuned!

ResearchBlogging.org
Higgins, E. T. (1997). Beyond pleasure and pain American Psychologist (52), 1280-1300

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Friday, October 03, 2008

Magical thinking and feelings of control

A recent article in Science Magazine relates Magical thinking to feelings of control. It is an interesting paper and here is the abstract:


We present six experiments that tested whether lacking control increases illusory pattern perception,which we define as the identification of a coherent and meaningful interrelationship among a set of random or unrelated stimuli. Participants who lacked control were more likely to perceive a variety of illusory patterns, including seeing images in noise, forming illusory correlations in stock market information, perceiving conspiracies, and developing superstitions. Additionally, we demonstrated that increased pattern perception has a motivational basis by measuring the need for structure directly and showing that the causal link between lack of control and illusory pattern perception is reduced by affirming the self. Although these many disparate forms of pattern perception are typically discussed as separate phenomena, the current results suggest that there is a common motive underlying them.

More discussion of the studies can be found at Mind Hacks and Psychology Today Blog Brainstorm

To me, it is exciting that Magical thinking  and feelings of control are linked together. It is my thesis that Manic episodes and frank psychosis are marked by presence of Magical Thinking to a large and  non-adaptive degree.  Sometimes severe depression too causes Psychosis and I presume that Magical thinking in that case too may be increased. If so, one of the frameworks for understanding depression is that of learned helplessness paradigm , whereby mice are exposed to uncontrollable shocks and then do not even try to avoid the shocks , even after the external environment has changed and they could now possibly avoid them by correct behaviour. One explanation for psychosis in severe depression may be that feelings of lack of control rise to such a level that one starts indulging in Magical thinking and starts creating and seeing patterns that are not there and thus loosing touch with Reality. 

This raises another question of whether Manic psychosis may itself be due to the same stress and feelings of non-control, but this time not leading to Depression but Mania. We all know that bipolarity is a stress-diatheisis model and maybe whenever stress causes feelings of lack of control the bipolar people have a tendency to exaggerated magical thinking: When mood is good this may lead to Manic psychosis; while when mood is low the same magical thinking may lead to depressive psychosis. Does anyone know any literature on bipolar people being more magical thinkers? does the same reason also work well for them and endow them with creativity? Another related question would be whether bipolar people have more feelings of being out of control? And what about self-esteem, do those in Mania , who get psychosis, also suffer from lack of self-esteem and this is mediated by the role of self-esteem in protecting against magical thinking? 
    

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Wednesday, March 12, 2008

Magical Thinking

There is an interesting article in Psychology Today regarding Magical Thinking and though one should read it in its entirety, I'll also post some snippets.


1. Anything can be sacred.
What makes something sacred is not its material makeup but its unique history. And whatever causes us to value essence over appearance becomes apparent at an early age. Psychologists Bruce Hood at Bristol University and Paul Bloom at Yale convinced kids ages 3 to 6 that they'd constructed a "copying machine." The kids were fine taking home a copy of a piece of precious metal produced by the machine, but not so with a clone of one of Queen Elizabeth II's spoons—they wanted the original.

2. Anything can be cursed.
Essences are not always good. In fact, people show stronger reactions to negative taint than to positive. Mother Teresa cannot fully neutralize the evil in a sweater worn by Hitler, a fact that fits the germ theory of moral contagion: A drop of sewage does more to a bucket of clean water than a drop of clean water does to a bucket of sewage. Traditional cleaning can't erase bad vibes either. Studies by Rozin and colleagues show that people have a strong aversion to wearing laundered clothes that have been worn by a murderer or even by someone who's lost a leg in an accident.

3. Mind rules over matter.
Wishing is probably the most ubiquitous kind of magical spell around, the unreasonable expectation that your thoughts have force and energy to act on the world. Emily Pronin and colleagues at Princeton and Harvard convinced undergrads in a study that they had put voodoo curses on fellow subjects. While targeting their thoughts on the other students, hexers pushed pins into voodoo dolls and the "victims" feigned headaches. Some victims had been instructed to behave like jackasses during the study (the "Stupid People Shouldn't Breed" T-shirt was a nice touch), eliciting ill will from pin pushers. Those who dealt with the jerks felt much more responsible for the headaches than the control group did. If you think it, and it happens, then you did it, right? Pronin describes the results as a particular form of seeing causality in coincidence, where the "cause" is especially conspicuous because it's hard to miss what's going on in your own head.


4. Rituals bring good luck.
To witness the mindless repetition of actions with no proven causal effect, there's no better laboratory than the athletic field.
We use ritual acts most often when there is little cost to them, when an outcome is uncertain or beyond our control, and when the stakes are high—hence my communion with the fuselage. People who truly trust in their rituals exhibit a phenomenon known as "illusion of control," the belief that they have more influence over the world than they actually do. And it's not a bad delusion to have—a sense of control encourages people to work harder than they might otherwise. In fact, a fully accurate assessment of your powers, a state known as "depressive realism," haunts people with clinical depression, who in general show less magical thinking.

5. To name is to rule.
Just as thoughts and objects have power, so do names. Language's ability to dredge up associations acts as a spell over us. Piaget argued that children often confuse objects with their names, a phenomenon he labeled nominal realism. Rozin and colleagues have demonstrated nominal realism in adults. After watching sugar being poured into two glasses of water and then personally affixing a "sucrose" label to one and a "poison" label to the other, people much prefer to drink from the "sucrose" glass and will even shy away from one they label "not poison." (The subconscious doesn't process negatives.)

6. Karma's a bitch.
Belief in a just world puts our minds at ease: Even if things are beyond our control, they happen for a reason. The idea of arbitrary pain and suffering is just too much for many people to bear, and the need for moral order may help explain the popularity of religion; in fact, just-worlders are more religious than others. Faith in cosmic jurisprudence starts early. Harvard psychologists showed that kids ages 5 to 7 like a child who found $5 on the sidewalk more than one whose soccer game got rained out

7. The world is alive.
To believe that the universe is sympathetic to our wishes is to believe that it has a mind or a soul, however rudimentary. We often see inanimate objects as infused with a life force.Lindeman Marjaana, a psychologist at the University of Helsinki, defines magical thinking as treating the world as if it has mental properties (animism) or expecting the mind to exhibit the properties of the physical world. She found that people who literally endorse phrases such as, "Old furniture knows things about the past," or, "An evil thought is contaminated," also believe in things like feng shui (the idea that the arrangement of furniture can channel life energy) and astrology. They are also more likely to be religious and to believe in paranormal agents.


In the end they also list the benefits of magical thinking and how some magical thinking has indeed proved somewhat correct!!

Who are WE to say the dreamers have it wrong? Carol Nemeroff and Paul Rozin point out that many magical beliefs have gained some element of scientific validity:

  • Magical contagion: Germ theory has shown that we have reason to fear that something invisible and negative can be transmitted by contact. Bacteria are the new curses.
  • Holographic existence: The idea that the whole is contained in each of its parts is born out by biology. Every cell in your body contains all of the DNA needed to create an entire person.
  • Action at a distance: Can voodoo dolls and magic wands have an impact? Well, gravitational pull works at a distance. So do remote controls, through electromagnetic radiation.
  • Mind over matter: The placebo effect is well-documented. Just thinking that an inert pill will have a medical effect on you makes it so.
  • Mana: Mana is the Polynesian term for the ubiquitous concept of communicable supernatural power. There is indeed a universally applicable parcel of influence that is abstract and connects us all: money.
Overall, an interesting piece indeed.

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Wednesday, January 30, 2008

good mood= intuition + good mood = psychosis?

I recently blogged about how good mood may lead to diminishing of working memory and I have blogged in the past regarding how good mood + intuitive thinking styles may lead to Magical thinking.

Now there appears a new study that shows that good mood, in and of itself, may lead to more reliance on Intuition or conscious gut feelings while making decisions. DeVries et al use the Iowa Gambling Task to ascertain whether an experimental manipulation (watching 2.5 minutes happy or sad clips) affected the performance on the IGT, in the window (20 to 40 cards from start) when the participants were using the conscious gut feeling or intuition to form their decisions . What they found was that a good or happy mood made the people rely more on their intuitive or conscious gut feelings vis-a-vis controls and the negative mood had the opposite effect of making them more deliberative. This was reflected in respectively good and poor performance on the second block of trial in the two affect cases . I present below the abstract of the study.

The present research aimed to test the role of mood in the Iowa Gambling Task . In the IGT, participants can win or lose money by picking cards from four different decks. They have to learn by experience that two decks are overall advantageous and two decks are overall disadvantageous. Previous studies have shown that at an early stage in this card-game, players begin to display a tendency towards the advantageous decks. Subsequent research suggested that at this stage, people base their decisions on conscious gut feelings. Based on empirical evidence for the relation between mood and cognitive processing-styles, we expected and consistently found that, compared to a negative mood state, reported and induced positive mood states increased this early tendency towards advantageous decks. Our results provide support for the idea that a positive mood causes stronger reliance on affective signals in decision-making than a negative mood.


I tend to put this in a broader context and it is apparent to me that good mood leads to more reliance and usage of intuitive thinking styles. this may even be mediated by the fact that working memory deficits associated with good mood prevent a deliberative approach to problem solving and instead favors an affective driven or intuitive approach. Taken together this implies that good mood leads to more intuitive thinking and decision making style. However, we have seen earlier that good mood and an intuitive thinking style are a dangerous mixture and lead to Magical thinking styles. Taken together this would mean that good mood induces a positive runaway process that causes more reliance on intuitive thinking which causes more
Magical thinking style and ultimately the good mood spirals upwards from good mood to Mania to full blown psychosis. I am excited by these linkages as they may provide additional points of attack where one can address the cognitive factors behind Mania / Psychosis and lead to additional therapeutic paradigms. How about you? Does this correlation and causation form Mood to Intuition to Magical thinking excite you too?

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Monday, January 28, 2008

good mood= compromised working memory?

A recent study mentions that when people are in good mood, they are likely to choose from amongst the first of the options presented, if asked to choose on the run. However, if they are asked to withhold evaluation till all the alternatives are presented, then they chose the last item presented.

A new study in the February issue of the Journal of Consumer Research people finds that consumers in a good mood are more likely than unhappy consumers to choose the first item they see, especially if all the choices are more or less the same.

The researchers also found that when happy consumers were asked to withhold judgment until all options were presented, they tended to prefer the last option they saw.


To me this appears very much like the recency and primacy effects. Their working memory is so much compromised , due to their good mood that they resort to the heuristics of recency/ primacy to determine their decisions.

The above theory may seem outrageous at first glance, but there are studies suggesting that people are bad decision makers when in good mood and that working memory compromise may be the underlying factor.

A good mood may be bad for people faced with problem-solving tasks that demand a high degree of logical thought and planning, according to a study.

Researchers say the brain may be too busy retrieving "feelgood" memories to enhance the positive mood to focus fully on the task in hand. Someone in a neutral mood can devote themself solely to problem solving, they argue.


According to Mike Oswald, when in good mood, good memories are brought into consciousness and this intrudes with the limited working memory thus temporarily incapacitating it.

Dr Oaksford, who will receive the BPS Spearman Medal today for his work on human reasoning, said that the positive mood state may be affecting the brain's capacity for "working memory" - a space devoted to thinking, planning, and problem solving - as good memories are being retrieved at the same time.

"It is like a having a blackboard to work your problems out on but your memory is writing on that blackboard at the same time," he said


This compromising of working memory due to good mood may also explain the working memory deficits found in those suffering from Mania/ psychosis. This may also underlie their jumping to conclusions sort of thinking as they pick the first alternative that comes to mind. Also this may explain their irritable and impatient mood, where they just go for decision making without withholding judgment as the first option itself seems promising and does not get critical evaluation. The direction may even be reverse- due to irritability and good mood (manic style) associations, one may choose the first alternative and this may appear like the primacy effect. However the directionality may be it seems evident that good mood comes accompanied with bad decisions. If the relation is exclusively that of working memory overrode with primacy and recency heuristics we can devise better decision making guidelines for those suffering from Mania.

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Wednesday, February 28, 2007

The Mind - Brain dichotomy: What it means to have a mind

Researchers at Harvard, Gray et al, are conducting an ongoing mind survey, and have also reported some findings from that online survey, based ona asmaple of more than 2,000 people.

The survey attempts to make one think about different forms of entities that may have a mind and to assign different degrees of consciousness/ mind on them.

Gray worked alongside fellow psychologists Heather Gray and Daniel Wegner on the study, which presented respondents with 13 characters: 7 living human forms (7-week-old fetus, 5-month-old infant, 5-year-old girl, adult woman, adult man, man in a persistent vegetative state, and the respondent himself or herself), 3 non-human animals (frog, family dog, and wild chimpanzee), a dead woman, God, and a sociable robot.

Participants were asked to rate the characters on the extent to which each possessed a number of capacities, ranging from hunger, fear, embarrassment, and pleasure to self-control, morality, memory and thought. Their analyses yielded two distinct dimensions by which people perceive the minds of others, agency and experience.

The participants attribute different degrees of these factors to the characters based on a forced choice between a pair of characters on a particular ability related to a mind capacity like feeling fear or making moral decisions. I believe they than id factor analysis or some such statistical method to come up with two independent dimensions or factor underlying the concept of mind: Agency or Experience.

Agency seems to be related to the fact that people (entities with mind) can take volitional actions and are thereby responsible for their actions. They can thus also be judged morally based on their actions and the choices they make.

Experience seems related to the fact that people (entities with mind) have an ability to feel and are emotional entities that have subjective experience of emotions like pain, fear and hunger and also have desires, longings and feelings etc.

The ability to perceive qualia surprisingly didn't come out as a separate entity and consciousness or ability to perceive qualia is supposedly covered under the Experience factor.

These dimensions are independent: An entity can be viewed to have experience without having any agency, and vice versa. For instance, respondents viewed the infant as high in experience but low in agency -- having feelings, but unaccountable for its actions -- while God was viewed as having agency but not experience.

"Respondents, the majority of whom were at least moderately religious, viewed God as an agent capable of moral action, but without much capacity for experience," Gray says. "We find it hard to envision God sharing any of our feelings or desires."


The regular readers of this blog will remember that one of the important distinction that I hypothesized between Schizophrenia and Autism was that due to agency: with schizophrenics attributing too much Agency; and Autistic attributing too less Agency to others (other people or other entities that may have mind). Also as God is perceived as having too much Agency, but not much Experience, thus when the Schizophrenia end of spectrum kicks in, they may also attribute too much agency to themselves and feel God-like or Divine. The negative symptoms related to less of experience would also fit the fact of being God-like or being an angel/ special person and thus not having too much emotions. The Autistic end of the spectrum however would be guided by too-less-mind sort of attributions and thinking; and thus they may view themselves and others as brains and not minds. They might thus be more capable with inanimate objects and rules of nature (thus making them good scientists/ engineers/ systemizers) ; but poor at social/ ethical aspects that require attributing minds to animals for example.

One should also distinguish between the two dimensions of Agency and Experience. Thus Autistic may have a defect due to Agency, but may have mirror neurons or other systems that confer on them the ability to feel , not only subjective feelings of self - but empathetic feelings of others too.

Also, it has been this blogs contention that the Dimension of experience is best seen as a dimension on one end of which is the Bipolar patients and on the other end of which is the Deprosanalisation/ apathetic / derealization spectrum. while the Bipolar feels too much emotions and motivations; the depersonalised/ derealized person may show too less emotion/ motivation.

Thus in mind at one end we have people having too much mind/ believing in too much mind (and exemplified by Schizophrenic and Bipolar ) and at the other end we have too people having too much brain/ believing in too much brain (exemplified by Autistic/ depersonalised people). One gives great Art, the other great Science.

Returning to the current study:

"The perception of experience to these characters is important, because along with experience comes a suite of inalienable rights, the most important of which is the right to life," Gray says. "If you see a man in a persistent vegetative state as having feelings, it feels wrong to pull the plug on him, whereas if he is just a lump of firing neurons, we have less compunction at freeing up his hospital bed."

This is exactly one of the pertinent point made by the film Munnabhai MBBS- that coma patients have feelings and have a right of life. While I have featured the effects of Lage Raho Munnabhai earlier; I would also like to pay tribute to its prequel/ precursor.

On that note, let us keep our antennas up for how thinking about us as entities with Agency and Experince can lead to Art; while thinking of us as brains can lead to good scince. I'm sure you'll agree that we need both of these concepts about us humans.


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Friday, February 23, 2007

Catch 22: Psychosis, Culture and the Mind Wars

While the original catch 22 was about a person not getting interned for military service on a premise that one is insane and thus incapable; and on the flip side the fact that only a sane person , who wants to avoid military service , would use such an insanity defense; this post is more about the fact that if psychosis/delusion is defined in cultural terms, then a society of affected individuals who form a community/culture in which their beliefs/ behavior is not considered bizarre would have cured themselves of their malady by just forming a community.

Thus the paradox of defining psychotic symptoms in relative terms -

  • socially inappropriate behavior- As an example - if a person gets nude, it is a socially inappropriate behavior; but if he joins and starts living on a private nude beach- that becomes an acceptable behavior.
  • delusions as beliefs not shared by the community/culture - as Vaughan from Mind Hacks points out in his original research - here people with mind control delusions form an online community and thus logically within their community/ sub-culture- their beliefs are no more illogical or delusional.
  • Hallucinations as visions/ voices not heard/seen by others- This has an inherent problem as the qualia one experiences cannot be shared by others. Suppose one sees a magical performance in which something impossibles happens in front of one's eyes - like a man cutting himself in two-is that a real phenomenon as all the audiences have witnessed it. Conversely if someone sees or hears things that seem more real than real to him/her but are not perceived by others should he doubt his subjective experience? If many psychotic patients come together and by synchronising in some sense of the word , get an auditory/ visual hallucination simultaneously - would that make their case strong that they are not listening to imaginary voices? As the diagnosis is made based on the presence of hallucinations and the psychiatrists are usually least bothered about the content, should it matter that the voice they hear says the same thing?
I concur with Vaughan that diagnosis not be made on relative terms - it should be in absolute terms. A behavior of being nude in public is no more appropriate- it once was when we were evolving- but now that we have clothes we better cover ourselves and if we have to reveal , reveal in a socially acceptable context (for eg Jain Munis or other saints at times go about naked, because the culture/ community of these holy men is very different from ours).

Similarly, delusions may just be an attempt to weave a coherent narrative around their unusual experiences- if the prevailing culture's main values are things like warfare/ exploitation/ mind control experiments , then when faced with immense stressful situations that may lead to physcila and chemical changes in the brain and behavior and sensorimotor gating, one may cope by rationalizing one's state as due to mind-control . Alternately one may consider oneself a victim of alien abduction and as being controlled by Aliens if the culture of that person values more of science and futuristic scenarios. Alternately the person from religious and spiritual cultures may believe themselves to be controlled by God or Satan and being juts the vehicle for their wishes. I have my own preferences and prejudices as to which interpretation is more desirable, but I'll leave that for now and caution that it is best to consider a delusional belief as efforts to make sense of their unusual experincecs an tackled as such. One knows that the psychosis gets triggered by stress and emotional turmoil and one should address that to prevent the emergence of symtoms and then address the delusional beliefs.

I would now like to draw attention to an article I read in Washington post today. The author meets up with some Targeted Individual (TIs) of mind-control community and comes up with some very interesting observations.

The callers frequently refer to themselves as TIs, which is short for Targeted Individuals, and talk about V2K -- the official military abbreviation stands for "voice to skull" and denotes weapons that beam voices or sounds into the head. In their esoteric lexicon, "gang stalking" refers to the belief that they are being followed and harassed: by neighbors, strangers or colleagues who are agents for the government.


I am currently reading a book Mind Wars by Moreno and one reason I am a bit reluctant to do a quick review is because it brings to light many such mind-control and man-machine intelligence experiments that may fuel mind-control delusions in those at risk and those trying to make sense of their stressful and emotional experiences . The book has similarly been written on a very cautious note, and I would love to review it also in a cautious mode. For now on to the Washington post article.

For all the scorn, the ranks of victims -- or people who believe they are victims -- are speaking up. In the course of the evening, there are as many as 40 clicks from people joining the call, and much larger numbers participate in the online forum, which has 143 members. A note there mentioning interest from a journalist prompted more than 200 e-mail responses.

It is interesting to note that the number of forum members is close to 150 - the number most frequently associated with any active community- as is also the number of nodes that cluster together in a real small-world network. Vaughan also points that the social network they discovered , by analyzing online mind-control sites, was a small-world network.

Girard sought advice from this then-girlfriend, a practicing psychologist, whom he declines to identify. He says she told him, "Nobody can become psychotic in their late 40s." She said he didn't seem to manifest other symptoms of psychotic behavior -- he dressed well, paid his bills -- and, besides his claims of surveillance, which sounded paranoid, he behaved normally. "People who are psychotic are socially isolated," he recalls her saying.


This exposes some of the frequent myths associated with Psychosis. As one relates psychosis most with Schizophrenia, one believes that it cannot occur later- if one thinks of schizophrenia as a extreme manic episode of a bipolar disorder, one would not have a bias. Interestingly, of the blind psychiatrist that analyzed the online sites in the Vaughan study , most made an outright diagnosis of schizophrenia and not a delusional or psychotic assessment. Again, those having bipolar disorder may not be socially isolated. Even bipolar patients can suffer from mind-control or other delusions.

He got the same response from friends, he says. "They regarded me as crazy, which is a humiliating experience."

When asked why he didn't consult a doctor about the voices and the pain, he says, "I don't dare start talking to people because of the potential stigma of it all. I don't want to be treated differently. Here I was in Philadelphia. Something was going on, I don't know any doctors . . . I know somebody's doing something to me."

Again notice the downward spiral - to avoid stigma and humiliation (at both being diagnosed as mad and putting one's family to risk and shame(genetic defect) and as being not able to cope with external stresses( a perceived character defect) one takes the other more acceptable alternative of explaining one's predicament as a result of prevalent cultural values. This leads to loss of touch with reality and pardoxically leads to social unaccepatnce. Here it is imperative to note that in some other psychological conditions like Mass hysteria too- the content of the abnormal behavior comprises of and is affected by prevalent cultural values. One may thus have a control-by-god 'delusion' or a control-by-govt/machines delusion or a control-by-aliens delusions. nbe may even see visions accordingly- some of a deity, others of Significan Others and still others of Govt agents (remember A Beautiful Mind).

Girard, for his part, believes these weapons were not only developed but were also tested on him more than 20 years ago.

What would the government gain by torturing him? Again, Girard found what he believed to be an explanation, or at least a precedent: During the Cold War, the government conducted radiation experiments on scores of unwitting victims, essentially using them as human guinea pigs. Girard came to believe that he, too, was a walking experiment.

As long as things like these have happened historically, one should not be surprised if one becomes suspicious after meeting top govt personnels at a stressful and vulnerable time. Also remember the LCD experiments!

GIRARD'S STORY, HOWEVER STRANGE, reflects what TIs around the world report: a chance encounter with a government agency or official, followed by surveillance and gang stalking, and then, in many cases, voices, and pain similar to electric shocks. Some in the community have taken it upon themselves to document as many cases as possible. One TI from California conducted about 50 interviews, narrowing the symptoms down to several major areas: "ringing in the ears," "manipulation of body parts," "hearing voices," "piercing sensation on skin," "sinus problems" and "sexual attacks." In fact, the TI continued, "many report the sensation of having their genitalia manipulated."

Again psychiatrists typically ignore the content of delusions/ hallucinations, but it is apparent that their is a pattern. I hope I was qualified enough to comment on what may be behind this pattern, but hopefully others more qualified would take a lead here and start examining why the etiology should be like this. One explanation, that is apparent is , treating one's body reactions as being caused by others.

What made her think it was an electronic attack and not just in her head? "There was no sexual attraction to a man when it would happen. That's what was wrong. It did not feel like a muscle spasm or whatever," she says. "It's so . . . electronic."

Again, it is plausible that the attraction is unconscious and one is trying to make sense of a consciously undesired sensation.

Like Girard, Naylor describes what she calls "street theater" -- incidents that might be dismissed by others as coincidental, but which Naylor believes were set up. She noticed suspicious cars driving by her isolated vacation home. On an airplane, fellow passengers mimicked her every movement -- like mimes on a street.


Again if we have cultural artifacts like Bertolt Brescht type street theatres, MTV bakras or the concept of psychodramas, then it is quite possible that these delusions of conspiracy may get woven in the narrative.

For almost four years, Naylor says, the voices prevented her from writing. In 2000, she says, around the time she discovered the mind-control forums, the voices stopped and the surveillance tapered off. It was then that she began writing 1996 as a "catharsis."

Colleagues urged Naylor not to publish the book, saying she would destroy her reputation. But she did publish, albeit with a small publishing house. The book was generally ignored by critics but embraced by TIs.

Naylor is not the first writer to describe such a personal descent. Evelyn Waugh, one of the great novelists of the 20th century, details similar experiences in The Ordeal of Gilbert Pinfold. Waugh's book, published in 1957, has eerie similarities to Naylor's.

Again notice the stigma and the similarities.

Embarking on a recuperative cruise, Pinfold begins to hear voices on the ship that he believes are part of a wireless system capable of broadcasting into his head; he believes the instigator recruited fellow passengers to act as operatives; and he describes "performances" put on by passengers directed at him yet meant to look innocuous to others.

"One tries to convince friends and family that you are being electronically harassed with voices that only you can hear," he writes in an e-mail. "You learn to stop doing that. They don't believe you, and they become sad and concerned, and it amplifies your own depression when you have voices screaming at you and your friends and family looking at you as a helpless, sick, mentally unbalanced wreck."

Moore, like other TIs, is cautious about sharing details of his life. He worries about looking foolish to friends and colleagues -- but he says that risk is ultimately worthwhile if he can bring attention to the issue.


More stigma. And More courage, but perhaps in the wrong direction.

Alexander acknowledged that "there were some abuses that took place," but added that, on the whole, "I would argue we threw the baby out with the bath water."

But September 11, 2001, changed the mood in Washington, and some in the national security community are again expressing interest in mind control, particularly a younger generation of officials who weren't around for MK-ULTRA. "It's interesting, that it's coming back," Alexander observed.

"Maybe I can fix you, or electronically neuter you, so it's safe to release you into society, so you won't come back and kill me," Alexander says. It's only a matter of time before technology allows that scenario to come true, he continues. "We're now getting to where we can do that." He pauses for a moment to take a bite of his sandwich. "Where does that fall in the ethics spectrum? That's a really tough question."

When Alexander encounters a query he doesn't want to answer, such as one about the ethics of mind control, he smiles and raises his hands level to his chest, as if balancing two imaginary weights. In one hand is mind control and the sanctity of free thought -- and in the other hand, a tad higher -- is the war on terrorism.

Does 9/11 justify a preparedness for Mind Wars? Or is the root of all evil in the culture that puts inappropriate stress on vulnerable individuls. It is interesting to note that some people got rid of their symptoms after joining online support groups.
Clancy argues that the main reason people believe they've been abducted by aliens is that it provides them with a compelling narrative to explain their perception that strange things have happened to them, such as marks on their bodies (marks others would simply dismiss as bruises), stimulation to their sexual organs (as the TIs describe) or feelings of paranoia. "It's not just an explanation for your problems; it's a source of meaning for your life," Clancy says.

In the case of TIs, mind-control weapons are an explanation for the voices they hear in their head. Socrates heard a voice and thought it was a demon; Joan of Arc heard voices from God. As one TI noted in an e-mail: "Each person undergoing this harassment is looking for the solution to the problem. Each person analyzes it through his or her own particular spectrum of beliefs. If you are a scientific-minded person, then you will probably analyze the situation from that perspective and conclude it must be done with some kind of electronic devices. If you are a religious person, you will see it as a struggle between the elements of whatever religion you believe in. If you are maybe, perhaps more eccentric, you may think that it is alien in nature."

A step towrads the right solutions.

Being a victim of government surveillance is also, arguably, better than being insane. In Waugh's novella based on his own painful experience, when Pinfold concludes that hidden technology is being used to infiltrate his brain, he "felt nothing but gratitude in his discovery." Why? "He might be unpopular; he might be ridiculous; but he was not mad."

So is it better to be deluded or better to be Mad (psychotic).

In general, the outlook for TIs is not good; many lose their jobs, houses and family. Depression is common. But for many at the rally, experiencing the community of mind-control victims seems to help. One TI, a man who had been a rescue swimmer in the Coast Guard before voices in his head sent him on a downward spiral, expressed the solace he found among fellow TIs in a long e-mail to another TI: "I think that the only people that can help are people going through the same thing. Everyone else will not believe you, or they are possibly involved."

In the end, though, nothing could help him enough. In August 2006, he would commit suicide.

Grave lessons. Psychitric help is needed and required. An online community may prevent you from insanity; it doesnt prevent death and suicide.

Is there any reason for optimism?

Girard hesitates, then asks a rhetorical question.

"Why, despite all this, why am I the same person? Why am I Harlan Girard?"

For all his anguish, be it the result of mental illness or, as Girard contends, government mind control, the voices haven't managed to conquer the thing that makes him who he is: Call it his consciousness, his intellect or, perhaps, his soul.

"That's what they don't yet have," he says. After 22 years, "I'm still me."


The last words of hope. At least we are not lobotomizing people now and making them a different person.

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Schizophrenia and Bipolar disorder: The propensity towards psychosis

Schizophrenia, as we all know, is one of the most dibilating psychological disorder. It was primarily conceived of as a behavioral disorder, characterized by socially inappropriate and bizarre behavior, but much attention has been focussed nowadays on the cognitive component and the cognitive pathology underlying schizophrenia and it is not unusual for it to be characterized as a thought disorder nowadays .

Bipolar , or Manic Depressive disorder, on the other hand, has been primarily conceived of as a mood or affective disorder , characterized by excessive swings of emotion and motivation. One of my earlier post had tried to analyze the cognitive components involved in the Bipolar condition, and relate it to that found in unipolar depression.

While in my earlier posts, I have discussed the differences between the social and communicative difficulties of Autistic and Schizophrenic probands, especially in relation to their different cognitive styles, and how a milder form of such thinking can lead to different types of creativity, I had also promised for a similar dichotomous discussion of bipolarity at one end of the spectrum and depersonalization/ derealization/ 'Alienation' on the other hand- this time the important dimension being the feeling/emotion/motivation dimension.

While that discussion still awaits, I have come across a fascinating article by Lake et al(freely available, registration required) that tries to analyze the schizophrenic and bipolar type I disorders and concludes that there is no such thing as schizophrenia - the psychosis underlying schizophrenia, schizoaffcetive and Bipolar disorders is actually due to a not-yet-diagnosed Bipolar disorder in the patient. The extreme case of a Bipolar manic behavior would be a full-blown psychotic episode and in absence of proper assessment is likely to be diagnosed as schizophrenia. The article hopes, that identifying Bipolar in early stages would prevent unnecessary neuroleptics / anti-psychotics administration to the patient and prevent the significant side-effects of such medications and the rapid-cycling of the bipolar disorder itself, as mood stabilizers like Lithium and Valproate would not be given early on in the absence of bipolar diagnosis.

The other rationale for a single unified diagnosis of Bipolar is to prevent stigma associated with a diagnosis of schizophrenia. There has been well-documented research on the creativity-bipolar linkages; a similar research exists for creativity and schizotypal individuals- but due to the chronic, dibilating and adverse effects of a full-blown schizophrenic diagnosis , the literature about creativity and full-blown schizophrenia is limited (and perhaps inconclusive). The comprehensive ill-effects of a wrong diagnosis are given below:

For patient

  • Less likely to receive a mood stabilizer or antidepressant

  • Without a mood stabilizer, cycles increase and occur more rapidly; symptoms worsen

  • More likely to receive neuroleptics for life, increasing risk for severe and permanent side effects

  • Greater stigma with schizophrenia

  • Less likely to be employed

  • More likely to receive disability for life

  • More likely to “give up”

  For clinician

  • Increased risk of liability if patient given long-term neuroleptics instead of mood stabilizers develops tardive dyskinesia or commits suicide

The article takes a case study of a patient named Mr. C and tries to analyze how and why different diagnosis are made for the same patient depending on the presented symptoms and why Bipolar diagnosis occurs late in the cycle. Going through the case study may prove disheartening to many, and may make them skeptical of the whole psychiatry profession-leading to some anti-psychiatry rants too- yet one should realize that psychiatry is both an art as well as a science- asking the right question to get the patient (and disorder/ medication) history is very important. To appreciate this I would strongly recommend every body to read the "Selection of Antidepressant ' series on Corpus Callosum, which gives a fairly good idea of how psychiatrists make diagnosis in practice.

It is instructive to recall that we have earlier reported on a study that leads to common genetic markers for Psychosis and Mania- implying a single diagnosis, rather than a separate diagnosis of bipolarity or schizophrenia.

The article cites the following DSM-IV diagnostic criteria for Schizophrenia and explains how each is explicable as symptoms of extreme manic episode resulting in psychosis /depression.

Schizophrenia diagnosis6

Seen in psychotic mood disorders

Criterion A

  Hallucinations and delusions

50% to 80% explained by mood16,21

  Paranoia

Hides grandiosity4

  Catatonia

75% explained by mood7,8

  Disorganized speech and behavior

All patients with moderate to severe mania1-5

  Negative symptoms

All patients with moderate to severe depression4

Criterion B

  Social and job dysfunction

All patients with moderate to severe bipolar disorder5,13

Criterion C

  Chronic continuous symptoms

Patients can have psychotic symptoms continuously for 2 years to life5,6,13


I would like to pause here and group the symptoms of schizophrenia according to the basis they have:
  • A sensory basis (hallucinations etc, which may be due to senosrimotor gating as well as a lack of proper inhibition mechanisms; delusions of reference which may be due to inability to gate the inputs and thus end up treating everything as salient and consequently referring to self),
  • A cognitive basis (delusions - which may be due to extremes of normal cognitive biases that we all have - a manic delusion of grandeur- that may also lead paradoxically to delusions of paranoia( fear and suspicion) as one thinks of oneself as very special and hence vulnerable to the evil out there in the world)
  • A motor basis (catatonia - which may be due to problems with volitional control of motion- either too much control or too little- in one case ending up in the positions in which someone else has put them in- in the other remaining in the same position (samadhi in religious contexts) by exercising the will to move. Here again dopamine dysfunction would be relevant as it is involved in motor pathways.
  • A social/theory of mind basis (disorganized speech(flight of ideas) as one assumes too much ToM abilities in others and believes that the specifics one has left unsaid- and the abstract way in which one is talking - is comprehensible to others; disorganized behavior- which may be due to not taking social appropriateness into account as one is presumably on a very important mission on Earth.
  • An embodiment/ grounding basis and problems with agency(religiosity as one thinks of oneself as not grounded in the body and thus may lead to delusions of control and persecution (as a shadow that is embodied elsewhere is trying to control one) . Here metaphorical thinking and use of symbols as symbols for something else (an overarching idea) rather than referring to something out in the world may lead to loss with reality and magical thinking that takes too much correlation-is-causation kind of thinking and extends it to non-material and non-living things.
  • An Affective basis ( related to the fifth point for those who believe that emotions are due to body states) : the characteristic anhedonia , alogia and avolition. Symptoms that are similar in many ways to the symptoms of depressive state.
  • A Volitional basis (social and job dysfunction may be due to disturbances in the volitional system- too much goal direction (and where the goal happens to be not socially or work-place acceptable) leads to job dysfunction as does too less of goal-directed behavior.
  • Chronic nature: once neuroleptics are started one gets caught in the downward vicious circle. Also the nature of the disorder is cyclic just like the Bipolar with Positive symptoms more prominent in one phase and negative symptoms more prominent in the other phase. In between there can be remission and proper functioning.
Thus, I agree with the broad assessment of Lake et al, that most cases of schizophrenia may be juts an undiagnosed psychotic bipolar episode. Yet, I believe that schizophrenia is a heterogeneous disorder and there may be one or more sub-types. In my view schizophrenia proper leans more towards ToM/ social/ cognitive/ agency dysfunctions while Manic depressive is more about affective and volitional and recurrent dimensions. In my developmental framework; while the schizophrenic struggle with the first five developmental tasks; the bipolar struggle with the next three. Yet their common psychotic style confers susceptibility to psychosis in both cases. This would be as opposed to the same developmental challenges also faced by those with Autism/ depersonalization/ derelaization etc., who have an entirely different take on these issues. While one leans towards science (whose utility is well established); the other leans towards arts (whose utility is doubted sometimes), but which in my view is very important.

We are getting evidence of how emotions can affect decisions towards a better outcome and how having a framework that gives one a sense of meaning and purpose is essential. Science and evolutionary thinking at times robs us of these finer appreciations of life- at that time we do need a counter-dose of Art to keep us more grounded and to make life more enjoyable and worth living- even if that costs some people their sanity!! Maybe we need both GOD and evolution; both science and faith to keep us sane and on the right course.

Hat Tip: Neurofuture

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